Anti-TMEM16B antibody
Specifications
| Product Cat#: | AB-08-0108 |
| Product type: | Primary antibody |
| Antigen: | TMEM16B |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human ANO2. |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:800-1:2000); Immunohistochemistry (1:100-1:200) |
| Reactivity: | Human, Mouse, Rat |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | 1*PBS buffer (pH7.3), 50% Glycerol, 0.02% NaN3. |
| Purity: | Immunogen affinity purified |
| Storage: | Aliquot and freeze at -20°C. Avoid multiple freeze/thaw cycles. |
| Conjugate: | Unconjugated |
| Alternative names: | ANO2; Anoctamin 2; C12orf3; TMEM16B; Transmembrane Protein 16B (Eight Membrane-Spanning Domains); Anoctamin 2, Calcium Activated Chloride Channel; Transmembrane Protein 16B; Anoctamin-2; Chromosome 12 Open Reading Frame 3 |
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Target information
Calcium-activated chloride channel (CaCC) which may play a role in olfactory signal transduction. Odorant molecules bind to odor-sensing receptors (OSRs), leading to an increase in calcium entry that activates CaCC current which amplifies the depolarization of the OSR cells, ANO2 seems to be the underlying chloride channel involved in this process. May mediate light perception amplification in retina.
Provider
Erpantech Laboratory
