Anti-TMEM16A antibody
Specifications
| Product Cat#: | AB-06-4930 |
| Product type: | Primary antibody |
| Antigen: | TMEM16A |
| Immunogen: | Synthetic peptide within C-terminal human TMEM16A. |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:400-1000); Immunocytochemistry (1:100-1:200); Immunohistochemistry-Paraffin (1:100-200); Flow Cytometry (1:40-1:100) |
| Reactivity: | Human |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | 1*PBS buffer (pH7.4), 0.2% BSA, 50% Glycerol, 0.05% NaN3. |
| Concentration: | 1 mg/ml |
| Purity: | Immunogen affinity purified |
| Storage: | Aliquot and freeze at -20°C. Avoid multiple freeze/thaw cycles. |
| Conjugate: | Unconjugated |
| Alternative names: | ANO1; TAOS2; DOG1; TMEM16A; ORAOV2; Discovered On Gastrointestinal Stromal Tumors Protein 1; Anoctamin 1, Calcium Activated Chloride Channel; Tumor-Amplified And Overexpressed Sequence 2; Oral Cancer Overexpressed 2; Transmembrane Protein 16A; Anoctamin-1; FLJ10261; Transmembrane Protein 16A (Eight Membrane-Spanning Domains); Oral Cancer Overexpressed Protein 2; Calcium Activated Chloride Channel; Ca2+-Activated Cl- Channel |
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Target information
Calcium-activated chloride channel (CaCC) which plays a role in transepithelial anion transport and smooth muscle contraction. Required for the normal functioning of the interstitial cells of Cajal (ICCs) which generate electrical pacemaker activity in gastrointestinal smooth muscles. Acts as a major contributor to basal and stimulated chloride conductance in airway epithelial cells and plays an important role in tracheal cartilage development.
Provider
Erpantech Laboratory
