Anti-TLR9 antibody
Specifications
| Product Cat#: | AB-06-4374 |
| Product type: | Primary antibody |
| Antigen: | TLR9 |
| Immunogen: | Recombinant protein |
| Species immunized: | Mouse |
| Isotype: | IgG2a |
| Applications: | Western Blot (1:400-1:2000); Immunohistochemistry (1:40-1:200); Flow Cytometry (1:40-1:200); Immunocytochemistry (1:40-1:200) |
| Reactivity: | Human |
| Clonality (clone number): | Monoclonal (H2-B12) |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH 7.4), 1% BSA, 40% glycerol, 0.05% NaN3. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | CD 289 antibody |
| CD289 antibody | |
| TLR 9 antibody | |
| TLR9 antibody | |
| TLR9_HUMAN antibody | |
| Toll like receptor 9 antibody | |
| Toll like receptor 9 isoform A precursor antibody | |
| Toll like receptor 9 isoform B antibody | |
| Toll-like receptor 9 antibody |
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Target information
Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR9 is a nucleotide-sensing TLR which is activated by unmethylated cytidine-phosphate-guanosine (CpG) dinucleotides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Controls lymphocyte response to Helicobacter infection (By similarity). Upon CpG stimulation, induces B-cell proliferation, activation, survival and antibody production.
Provider
Erpantech Laboratory