Anti-TLR5 antibody
Specifications
| Product Cat#: | AB-06-4371 |
| Product type: | Primary antibody |
| Antigen: | TLR5 |
| Immunogen: | Recombinant protein |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:800-1:2000); Immunohistochemistry (1:40-1:200) |
| Reactivity: | Human, Mouse, Rat |
| Clonality (clone number): | Monoclonal (JM10-88) |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH 7.4), 1% BSA, 40% glycerol, 0.05% NaN3. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | FLJ10052 antibody |
| MGC126430 antibody | |
| MGC126431 antibody | |
| SLEB1 antibody | |
| TIL 3 antibody | |
| TIL3 antibody | |
| TLR 5 antibody | |
| Tlr5 antibody | |
| TLR5_HUMAN antibody | |
| Toll like receptor 5 antibody | |
| Toll like receptor 5 precursor antibody | |
| Toll-like receptor 5 antibody | |
| Toll/interleukin 1 receptor like protein 3 antibody | |
| Toll/interleukin-1 receptor-like protein 3 antibody |
Target information
Pattern recognition receptor (PRR) located on the cell surface that participates in the activation of innate immunity and inflammatory response. Recognizes small molecular motifs named pathogen-associated molecular pattern (PAMPs) expressed by pathogens and microbe-associated molecular patterns (MAMPs) usually expressed by resident microbiota. Upon ligand binding such as bacterial flagellins, recruits intracellular adapter proteins MYD88 and TRIF leading to NF-kappa-B activation, cytokine secretion and induction of the inflammatory response. Plays thereby an important role in the relationship between the intestinal epithelium and enteric microbes and contributes to the gut microbiota composition throughout life (By similarity).
Provider
Erpantech Laboratory
