Anti-TGF beta 3 propeptide antibody
Specifications
| Product Cat#: | AB-06-4319 |
| Product type: | Primary antibody |
| Antigen: | TGF beta 3 propeptide |
| Immunogen: | KLH conjugated synthetic peptide derived from human TGF-beta 3 propeptide 41-90/412 |
| Species immunized: | Human, Mouse, Rat, Dog, Pig, Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:400-1:2000); Immunohistochemistry-Paraffin (1:500-1:800) |
| Reactivity: | Human, Mouse, Rat |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | 10 mM Tris-HCl buffer (pH7.4), 1% BSA, 50% glycerol, 0.03% Proclin. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | TGF beta 3 |
| ARVD | |
| FLJ16571 | |
| MGC105479 | |
| MGC118722 | |
| TGF beta 3 | |
| TGF beta3 | |
| TGF-beta-3 | |
| TGF-beta 3 | |
| TGFB 3 | |
| TGFB3 | |
| TGFB3_HUMAN | |
| Transforming growth factor beta 3 |
Target information
Transforming growth factor beta-3 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-3 (TGF-beta-3) chains, which constitute the regulatory and active subunit of TGF-beta-3, respectively.
Latency-associated peptide: Required to maintain the Transforming growth factor beta-3 (TGF-beta-3) chain in a latent state during storage in extracellular matrix (By similarity). Associates non-covalently with TGF-beta-3 and regulates its activation via interaction with ‘milieu molecules’, such as LTBP1 and LRRC32/GARP, that control activation of TGF-beta-3 (By similarity). Interaction with integrins results in distortion of the Latency-associated peptide chain and subsequent release of the active TGF-beta-3 (By similarity).
Provider
Erpantech Laboratory
