Anti-Thioredoxin antibody
Specifications
| Product Cat#: | AB-06-4337 |
| Product type: | Primary antibody |
| Antigen: | Thioredoxin |
| Immunogen: | Peptide |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:400); Immunohistochemistry (1:40-1:100); Flow Cytometry (1:40-1:100); Immunocytochemistry (1:40-1:200) |
| Reactivity: | Human, Mouse |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4), 1% BSA, 40% glycerol, 0.05% NaN3. |
| Concentration: | 1 mg/ml |
| Purity: | Peptide affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | ADF antibody |
| ATL-derived factor antibody | |
| SASP antibody | |
| Surface associated sulphydryl protein antibody | |
| TRN antibody | |
| TXN 1 antibody | |
| TXN antibody |
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Target information
Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. Plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contributes to the response to intracellular nitric oxide. Nitrosylates the active site Cys of CASP3 in response to nitric oxide (NO), and thereby inhibits caspase-3 activity. Induces the FOS/JUN AP-1 DNA-binding activity in ionizing radiation (IR) cells through its oxidation/reduction status and stimulates AP-1 transcriptional activity.
ADF augments the expression of the interleukin-2 receptor TAC (IL2R/P55).
Provider
Erpantech Laboratory
