Anti-TCF3 antibody
Specifications
| Product Cat#: | AB-07-3860 |
| Product type: | Primary antibody |
| Antigen: | TCF3 |
| Immunogen: | A synthetic peptide derived from human TCF3. The exact amino-acid sequence is proprietary. |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:500~1:3000); ELISA (1:20000); Immunohistochemistry (1:50~1:100) |
| Reactivity: | Human, Mouse, Rat |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | PBS (without Mg2+ and Ca2+ ), pH 7.4, 150 mM NaCl, 0.02% sodium azide and 50% glycerol |
| Concentration: | 1 mg/ml |
| Purity: | Antigen affinity chromatography |
| Storage: | Aliquot and freeze at -20°C. Avoid multiple freeze/thaw cycles. |
| Alternative names: | E12, ITF1, Immunoglobulin enhancer binding factor E12/E47, Immunoglobulin transcription factor-1, Kappa-E2-binding factor, TCF-3, TCF3, TFE2, Transcription factor E2-alpha, Transcription factor ITF-1, Transcription factor-3 |
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Target information
Transcriptional regulator. Involved in the initiation of neuronal differentiation. Heterodimers between TCF3 and tissue-specific basic helix-loop-helix (bHLH) proteins play major roles in determining tissue-specific cell fate during embryogenesis, like muscle or early B-cell differentiation. Dimers bind DNA on E-box motifs: 5′-CANNTG-3′. Binds to the kappa-E2 site in the kappa immunoglobulin gene enhancer. Binds to IEB1 and IEB2, which are short DNA sequences in the insulin gene transcription control region.
Provider
Erpantech Laboratory
