Anti-TBCC antibody
Specifications
| Product Cat#: | AB-06-4282 |
| Product type: | Primary antibody |
| Antigen: | TBCC |
| Immunogen: | Recombinant protein |
| Species immunized: | Mouse |
| Isotype: | IgG1 |
| Applications: | Western Blot (1:400-1:2000); Immunohistochemistry (1:100-1:200); Immunocytochemistry (1:100-1:200) |
| Reactivity: | Human |
| Clonality (clone number): | Monoclonal |
| Form: | Liquid |
| Buffer: | 1*TBS (pH 7.4), 1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | Beta tubulin cofactor C antibody |
| CFC antibody | |
| TBCC antibody | |
| TBCC_HUMAN antibody | |
| Tubulin folding cofactor C antibody | |
| Tubulin specific chaperone c antibody | |
| Tubulin-folding cofactor C antibody | |
| Tubulin-specific chaperone C antibody |
Target information
Microtubules, the primary component of the cytoskeletal network, are highly dynamic structures composed of α/β Tubulin heterodimers. Biosynthesis of functional microtubules involve the participation of several chaperones, termed tubulin folding cofactors A (TBCA), D (TBCD), E (TBCE) and C (TBCC), that act on folding intermediates downstream of the cytosolic chaperonin, alternatively named TCP. TBCC (Tubulin-specific chaperone C), also known as β Tubulin-folding cofactor C or CFC, is a 346 amino acid protein belonging to the TBCD family. Interaction with TBCC causes the release of tubulin polypeptides that are committed to the native state. TBCC shares significant homology with X-linked retinitis pigmentosa 2 gene RP2, in which mutations cause the progressive degeneration of photoreceptor cells.
Provider
Erpantech Laboratory