Anti-ST5 antibody
Specifications
| Product Cat#: | AB-07-2141 |
| Product type: | Primary antibody |
| Antigen: | ST5 |
| Immunogen: | A synthetic peptide derived from internal of human ST5. The exact amino-acid sequence is proprietary. |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:500-1:2500); ELISA (1:15000) |
| Reactivity: | Human, Mouse |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodiumazide and 50% glycerol. |
| Concentration: | 1 mg/ml |
| Purity: | Antigen affinity chromatography |
| Storage: | Aliquot and freeze at -20°C. Avoid multiple freeze/thaw cycles. |
| Alternative names: | Suppression of tumorigenicity 5, HeLa tumor suppression 1, DENN domain-containing protein 2B, ST5, DENND2B, HTS1 |
Show More
Target information
May be involved in cytoskeletal organization and tumorogenicity. Seems to be involved in a signaling transduction pathway leading to activation of MAPK1/ERK2. Plays a role in EGFR trafficking from recycling endosomes back to the cell membrane (PubMed:29030480).2 Publications
Guanine nucleotide exchange factor (GEF) which may activate RAB9A and RAB9B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form.1 Publication
May block ERK2 activation stimulated by ABL1 (Probable). May alter cell morphology and cell growth (Probable).
Provider
Erpantech Laboratory
