Anti-SST antibody
Specifications
| Product Cat#: | AB-06-4192 |
| Product type: | Primary antibody |
| Antigen: | SST |
| Immunogen: | Purified recombinant fragment of human Somatostatin expressed in E. Coli. |
| Species immunized: | Mouse |
| Isotype: | IgG1 |
| Applications: | Western Blot (1:600-1:2000); Immunohistochemistry (1:60-1:200); Flow Cytometry (1:60-1:200) |
| Reactivity: | Human |
| Clonality (clone number): | Monoclonal (E7-G5) |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4), 1%BSA, Preservative: 0.05% Sodium Azide. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | Growth hormone release inhibiting factor antibody |
| Growth hormone release-inhibiting factor antibody | |
| Prepro somatostatin antibody | |
| SMS_HUMAN antibody | |
| SMST antibody | |
| Somatostatin 14 antibody | |
| Somatostatin 28 antibody | |
| Somatostatin-14 antibody | |
| SST antibody |
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Target information
Somatostatin-14: Inhibits the secretion of pituitary hormones, including that of growth hormone/somatotropin (GH1), PRL, ACTH, luteinizing hormone (LH) and TSH. Also impairs ghrelin- and GnRH-stimulated secretion of GH1 and LH; the inhibition of ghrelin-stimulated secretion of GH1 can be further increased by neuronostatin.1 Publication Neuronostatin: May enhance low-glucose-induced glucagon release by pancreatic alpha cells (By similarity). This effect may be mediated by binding to GPR107 and PKA activation (By similarity). May regulate cardiac contractile function (By similarity). May compromise cardiomyocyte viability (By similarity). In the central nervous system, may impair memory retention and may affect hippocampal excitability (By similarity). May also have anxiolytic and anorexigenic effects (By similarity). May play a role in arterial pressure regulation (By similarity). May inhibit basal, but not ghrelin- or GnRH-stimulated secretion of GH1 or LH, but does not affect the release of other pituitary hormones, including PRL, ACTH, FSH or TSH. Potentiates inhibitory action of somatostatin on ghrelin-stimulated secretion of GH1, but not that on GnRH-stimulated secretion of LH .
Provider
Erpantech Laboratory
