Anti-SOX2 Recombinant Rabbit Monoclonal antibody
Specifications
| Product Cat#: | AB-06-5053 |
| Product type: | Primary antibody |
| Antigen: | SOX2 |
| Immunogen: | Synthetic peptide within Human SOX2 AA 1-100 (N terminal). |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Immunohistochemistry-Paraffin (1:500-1000) |
| Reactivity: | Human, Rat |
| Clonality (clone number): | Monoclonal, PO00-29 |
| Form: | Liquid |
| Buffer: | 1*PBS buffer (pH7.4), 0.1% BSA, 40% Glycerol, 0.05% NaN3. |
| Concentration: | 1 mg/mL |
| Purity: | Protein A affinity purified. |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Conjugate: | Unconjugated |
| Alternative names: | ANOP3 antibody |
| cb236 antibody | |
| Delta EF2a antibody | |
| lcc antibody | |
| MCOPS3 antibody | |
| MGC148683 antibody | |
| MGC2413 antibody | |
| RGD1565646 antibody | |
| Sex determining region Y box 2 antibody | |
| SOX 2 antibody | |
| Sox2 antibody | |
| SOX2_HUMAN antibody | |
| SRY (sex determining region Y) box 2 antibody | |
| SRY box containing gene 2 antibody | |
| SRY related HMG box 2 antibody | |
| SRY related HMG box gene 2 antibody | |
| SRY-box 2 antibody | |
| Transcription factor SOX 2 antibody | |
| Transcription factor SOX-2 antibody | |
| ysb antibody |
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Target Information
Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues (PubMed:19022849).
Transcription factor activity is modulated by bound coactivator and corepressor proteins like ZBTB7A that recruits NCOR1 and NCOR2 to the androgen response elements/ARE on target genes, negatively regulating androgen receptor signaling and androgen-induced cell proliferation (PubMed:20812024).
Transcription activation is also down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3 and ZIPK/DAPK3
Provider
Erpantech Laboratory
