Anti-SOX2 antibody
Specifications
| Product Cat#: | AB-06-4156 |
| Product type: | Primary antibody |
| Antigen: | SOX2 |
| Immunogen: | Purified recombinant fragment of human SOX2 expressed in E. Coli. |
| Species immunized: | Mouse |
| Isotype: | IgG1 |
| Applications: | Western Blot (1:600-1:1000); Immunohistochemistry (1:80-1:500); Immunocytochemistry (1:60-1:200) |
| Reactivity: | Human |
| Clonality (clone number): | Monoclonal (C9-F10) |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | ANOP3 antibody |
| cb236 antibody | |
| Delta EF2a antibody | |
| lcc antibody | |
| MCOPS3 antibody | |
| MGC148683 antibody | |
| MGC2413 antibody | |
| RGD1565646 antibody | |
| Sex determining region Y box 2 antibody | |
| SOX 2 antibody | |
| Sox2 antibody | |
| SOX2_HUMAN antibody | |
| SRY (sex determining region Y) box 2 antibody | |
| SRY box containing gene 2 antibody | |
| SRY related HMG box 2 antibody | |
| SRY related HMG box gene 2 antibody | |
| SRY-box 2 antibody | |
| Transcription factor SOX 2 antibody | |
| Transcription factor SOX-2 antibody | |
| ysb antibody |
Target information
Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206 (By similarity). Critical for early embryogenesis and for embryonic stem cell pluripotency. May function as a switch in neuronal development. Downstream SRRT target that mediates the promotion of neural stem cell self-renewal (By similarity). Keeps
neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation (By similarity). Defects in SOX2 are the cause of microphthalmia syndromic type 3 (MCOPS3). Microphthalmia is a clinically heterogeneous disorder of eye formation, ranging from small size of a single eye to complete bilateral absence of ocular tissues (anophthalmia). In many cases, microphthalmia/anophthalmia occurs
in association with syndromes that include non-ocular
abnormalities
Provider
Erpantech Laboratory