Anti-SIX5 antibody
Specifications
| Product Cat#: | AB-07-2120 |
| Product type: | Primary antibody |
| Antigen: | SIX5 |
| Immunogen: | A synthetic peptide derived from internal of human SIX5. The exact amino-acid sequence is proprietary. |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:500-1:2500); ELISA (1:35000); |
| Reactivity: | Human, Mouse |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodiumazide and 50% glycerol. |
| Concentration: | 1 mg/ml |
| Purity: | Antigen affinity chromatography |
| Storage: | Aliquot and freeze at -20°C. Avoid multiple freeze/thaw cycles. |
| Alternative names: | DM locus-associated homeodomain protein; DMAHP; Homeobox protein SIX5 |
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Target information
Transcription factor that is thought to be involved in regulation of organogenesis. May be involved in determination and maintenance of retina formation. Binds a 5′-GGTGTCAG-3′ motif present in the ARE regulatory element of ATP1A1. Binds a 5′-TCA[AG][AG]TTNC-3′ motif present in the MEF3 element in the myogenin promoter, and in the IGFBP5 promoter (By similarity). Thought to be regulated by association with Dach and Eya proteins, and seems to be coactivated by EYA1, EYA2 and EYA3 (By similarity).
Provider
Erpantech Laboratory
