Anti-SFRP1 antibody
Specifications
| Product Cat#: | AB-06-4033 |
| Product type: | Primary antibody |
| Antigen: | SFRP1 |
| Immunogen: | Recombinant protein. |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:600-1:2000) |
| Reactivity: | Human |
| Clonality (clone number): | Monoclonal (JA11-68) |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | Frizzled related protein 1 antibody |
| FRP 1 antibody | |
| FRP antibody | |
| FRP-1 antibody | |
| FRP1 antibody | |
| FrzA antibody | |
| SARP 2 antibody | |
| SARP-2 antibody | |
| SARP2 antibody | |
| Secreted apoptosis related protein 2 antibody | |
| Secreted apoptosis-related protein 2 antibody | |
| Secreted frizzled related protein 1 antibody | |
| Secreted frizzled related protein antibody | |
| Secreted frizzled-related protein 1 antibody | |
| SFRP 1 antibody | |
| sFRP-1 antibody | |
| SFRP1 antibody | |
| SFRP1_HUMAN antibody |
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Target information
Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP1 decreases intracellular beta-catenin levels (By similarity). Has antiproliferative effects on vascular cells, in vitro and in vivo, and can induce, in vivo, an angiogenic response. In vascular cell cycle, delays the G1 phase and entry into the S phase (By similarity). In kidney development, inhibits tubule formation and bud growth in metanephroi (By similarity). Inhibits WNT1/WNT4-mediated TCF-dependent transcription.
Provider
Erpantech Laboratory
