Anti-SERPINE1 antibody
Specifications
| Product Cat#: | AB-06-4020 |
| Product type: | Primary antibody |
| Antigen: | SERPINE1 |
| Immunogen: | Purified recombinant fragment of human SERPINE1 expressed in E.Coli. |
| Species immunized: | Mouse |
| Isotype: | IgG1 |
| Applications: | Western Blot (1:600-1:1000); Immunohistochemistry (1:80-1:500); Flow Cytometry (1:80-1:200) |
| Reactivity: | Human, Mouse |
| Clonality (clone number): | Monoclonal (H9-D5) |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4), 1%BSA, Preservative: 0.05% Sodium Azide. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | Clade E antibody |
| Endothelial plasminogen activator inhibitor antibody | |
| Nexin antibody | |
| PAI 1 antibody | |
| PAI antibody | |
| PAI-1 antibody | |
| PAI1_HUMAN antibody | |
| PLANH1 antibody | |
| Plasminogen activator inhibitor 1 antibody | |
| Plasminogen activator inhibitor type 1 antibody | |
| Serine (or cysteine) proteinase inhibitor antibody | |
| Serine (or cysteine) proteinase inhibitor clade E (nexin plasminogen activator inhibitor type 1) member 1 antibody | |
| Serpin E1 antibody | |
| Serpin peptidase inhibitor clade E (nexin plasminogen activator inhibitor type 1) member 1 antibody | |
| Serpin peptidase inhibitor clade E antibody |
Target information
Serine protease inhibitor. Inhibits TMPRSS7 . Is a primary inhibitor of tissue-type plasminogen activator (PLAT) and urokinase-type plasminogen activator (PLAU). As PLAT inhibitor, it is required for fibrinolysis down-regulation and is responsible for the controlled degradation of blood clots . As PLAU inhibitor, it is involved in the regulation of cell adhesion and spreading. Acts as a regulator of cell migration, independently of its role as protease inhibitor . It is required for stimulation of keratinocyte migration during cutaneous injury repair . It is involved in cellular and replicative senescence . Plays a role in alveolar type 2 cells senescence in the lung (By similarity). Is involved in the regulation of cementogenic differentiation of periodontal ligament stem cells, and regulates odontoblast differentiation and dentin formation during odontogenesis .
Provider
Erpantech Laboratory
