Anti-SATB2 antibody
Specifications
| Product Cat#: | AB-06-3967 |
| Product type: | Primary antibody |
| Antigen: | SATB2 |
| Species immunized: | Mouse |
| Immunogen: | Recombinant protein |
| Isotype: | IgG |
| Applications: | Western Blot1:100-1:1,000; Immunoprecipitation:1-2 μg per 100-500 μg of total protein(1 ml of cell lysate); Immunofluorescence(1:50-1:500); Immunohistochemistry(1:50-1:500); Flow Cytometry :1 μg per 1 x 106 cells |
| Reactivity: | Human, Mouse, Rat |
| Clonality (clone number): | Monoclonal(4G03) |
| Form: | Liquid |
| Buffer: | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| Alternative names: | DNA binding protein SATB2 antibody |
| DNA-binding protein SATB2 antibody | |
| FLJ21474 antibody | |
| FLJ32076 antibody | |
| GLSS antibody | |
| KIAA1034 antibody | |
| MGC119474 antibody | |
| SATB family member 2 antibody | |
| SATB homeobox 2 antibody | |
| SATB2 antibody | |
| SATB2_HUMAN antibody | |
| Special AT rich sequence binding protein 2 antibody | |
| Special AT-rich sequence-binding protein 2 antibody |
Target information
Binds to DNA, at nuclear matrix- or scaffold-associated regions. Thought to recognize the sugar-phosphate structure of double-stranded DNA. Transcription factor controlling nuclear gene expression, by binding to matrix attachment regions (MARs) of DNA and inducing a local chromatin-loop remodeling. Acts as a docking site for several chromatin remodeling enzymes and also by recruiting corepressors (HDACs) or coactivators (HATs) directly to promoters and enhancers. Required for the initiation of the upper-layer neurons (UL1) specific genetic program and for the inactivation of deep-layer neurons (DL) and UL2 specific genes, probably by modulating BCL11B expression. Repressor of Ctip2 and regulatory determinant of corticocortical connections in the developing cerebral cortex. May play an important role in palate formation. Acts as a molecular node in a transcriptional network regulating skeletal development and osteoblast differentiation.
Provider
Erpantech Laboratory
