Anti-RNF6 antibody
Specifications
| Product Cat#: | AB-06-3902 |
| Product type: | Primary antibody |
| Antigen: | RNF6 |
| Immunogen: | KLH conjugated synthetic peptide derived from human RNF6 551-650/685 |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:500-1:2000) |
| Reactivity: | Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Sheep |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | 10 mM Tris-HCl buffer (pH7.4), 1% BSA, 50% Glycerol, 0.03% Proclin300. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| Alternative names: | E3 ubiquitin-protein ligase RNF6 |
| Ring finger protein (C3H2C3 type) 6 | |
| Ring finger protein 6 | |
| RING H2 protein | |
| RING H2 protein RNF6 | |
| RNF 6 | |
| RNF6 | |
| RNF6_HUMAN |
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Target information
E3 ubiquitin-protein ligase mediating ‘Lys-48’-linked polyubiquitination of LIMK1 and its subsequent targeting to the proteasome for degradation. Negatively regulates axonal outgrowth through regulation of the LIMK1 turnover. Mediates ‘Lys-6’ and ‘Lys-27’-linked polyubiquitination of AR/androgen receptor thereby modulating its transcriptional activity. May also bind DNA and function as a transcriptional regulator.
Provider
Erpantech Laboratory