Anti-RNF186 antibody
Specifications
| Product Cat#: | AB-06-3892 |
| Product type: | Primary antibody |
| Antigen: | RNF186 |
| Immunogen: | KLH conjugated synthetic peptide derived from human RNF186 31-130/227 |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:500-1:2000) |
| Reactivity: | Human, Mouse, Rat, Cow |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | 10 mM Tris-HCl buffer (pH7.4), 1% BSA, 50% Glycerol, 0.03% Proclin300. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| Alternative names: | FLJ20225 |
| Ring finger protein 186 | |
| RNF 186 | |
| RP11 91K11.1 | |
| RN186_HUMAN |
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Target information
E3 ubiquitin protein ligase that is part of an apoptotic signaling pathway activated by endoplasmic reticulum stress (PubMed:23896122). In that process, stimulates the expression of proteins specific of the unfolded protein response (UPR), ubiquitinates BNIP1 and regulates its localization to the mitochondrion and induces calcium release from the endoplasmic reticulum that ultimately leads to cell apoptosis (PubMed:23896122).
Provider
Erpantech Laboratory
