Anti-Rhodopsin antibody
Specifications
| Product Cat#: | AB-06-3869 |
| Product type: | Primary antibody |
| Antigen: | Rhodopsin |
| Immunogen: | Recombinant protein |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:500-1:1000); Immunohistochemistry (1:50-1:200) |
| Reactivity: | Human, Rat |
| Clonality (clone number): | Monoclonal (JA10-91) |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4), 1% BSA, 40% Glycerol, 0.05% NaN3. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| Alternative names: | CSNBAD1 antibody |
| MGC138309 antibody | |
| MGC138311 antibody | |
| OPN 2 antibody | |
| OPN2 antibody | |
| Opsd antibody | |
| OPSD_HUMAN antibody | |
| Opsin 2 antibody | |
| Opsin 2 rod pigment antibody | |
| Opsin-2 antibody | |
| Opsin2 antibody | |
| Retinitis Pigmentosa 4 antibody | |
| Retinitis pigmentosa 4 autosomal dominant antibody | |
| RHO antibody | |
| Rhodopsin antibody | |
| RP 4 antibody | |
| RP4 antibody |
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Target information
Photoreceptor required for image-forming vision at low light intensity (PubMed:8107847, PubMed:7846071). Required for photoreceptor cell viability after birth (PubMed:2215617, PubMed:12566452). Light-induced isomerization of the chromophore 11-cis-retinal to all-trans-retinal triggers a conformational change that activates signaling via G-proteins (PubMed:8107847, PubMed:28524165, PubMed:26200343, PubMed:28753425). Subsequent receptor phosphorylation mediates displacement of the bound G-protein alpha subunit by the arrestin SAG and terminates signaling (PubMed:28524165, PubMed:26200343).
Provider
Erpantech Laboratory
