Anti-RBM22 antibody
Specifications
| Product Cat#: | AB-06-3834 |
| Product type: | Primary antibody |
| Antigen: | RBM22 |
| Immunogen: | KLH conjugated synthetic peptide derived from human RBM22 101-300/420 |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:500-1:2000); Immunohistochemistry-Paraffin (1:400-1:800) |
| Reactivity: | Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | 10 mM TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| Alternative names: | Cwc2 |
| FLJ10290 | |
| fSAP47 | |
| Functional spliceosome associated protein 47 | |
| Pre mRNA splicing factor RBM22 | |
| Pre-mRNA-splicing factor RBM22 | |
| RBM 22 | |
| rbm22 | |
| RBM22_HUMAN | |
| RNA binding motif protein 22 | |
| RNA-binding motif protein 22 | |
| ZC3H16 | |
| Zinc finger CCCH domain containing protein 16 |
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Target information
Required for pre-mRNA splicing as component of the activated spliceosome (PubMed:28502770, PubMed:28076346, PubMed:29361316, PubMed:29360106, PubMed:29301961, PubMed:30705154). Involved in the first step of pre-mRNA splicing. Binds directly to the internal stem-loop (ISL) domain of the U6 snRNA and to the pre-mRNA intron near the 5′ splice site during the activation and catalytic phases of the spliceosome cycle. Involved in both translocations of the nuclear SLU7 to the cytoplasm and the cytosolic calcium-binding protein PDCD6 to the nucleus upon cellular stress responses.
Provider
Erpantech Laboratory
