Anti-PSMB7 Antibody
Specifications
| Product Cat#: | AB-06-4943 |
| Product type: | Primary antibody |
| Antigen: | PSMB7 |
| Immunogen: | Recombinant protein within Human PSMB7 aa 1-277/277. |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:250-1:500); Immunohistochemistry-Paraffin (1:500) |
| Reactivity: | Human |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | 1*PBS buffer (pH7.4), 0.1% BSA, 40% Glycerol, 0.05% NaN3. |
| Concentration: | 1 mg/ml |
| Purity: | Immunogen affinity purified. |
| Storage: | Aliquot and freeze at -20°C. Avoid multiple freeze/thaw cycles. |
| Conjugate: | Unconjugated |
| Alternative names: | Macropain chain Z antibody |
| Multicatalytic endopeptidase complex chain Z antibody | |
| Proteasome (prosome macropain) subunit beta type 7 antibody | |
| Proteasome beta 7 subunit antibody | |
| Proteasome catalytic subunit 2 antibody | |
| Proteasome subunit alpha antibody | |
| Proteasome subunit beta 7 antibody | |
| Proteasome subunit beta type-7 antibody | |
| Proteasome subunit Z antibody | |
| PSB7_HUMAN antibody | |
| PSMB7 antibody | |
| PUP1 antibody | |
| Z antibody |
Target information
Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required. Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation. This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex). Within the 20S core complex, PSMB7 displays a trypsin-like activity.
Provider
Erpantech Laboratory
