Anti-PSD95 antibody
Specifications
| Product type: | Primary antibody |
| Antigen: | PSD95 |
| Immunogen: | Peptide |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:1000); Immunohistochemistry (1:50) |
| Reactivity: | Mouse, Rat and Human |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Concentration: | 1mg/ml |
| Purity: | Peptide affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | Discs large homolog 4 antibody |
| Disks large homolog 4 antibody | |
| DLG 4 antibody | |
| Dlg4 antibody | |
| DLG4_HUMAN antibody | |
| FLJ97752 antibody | |
| FLJ98574 antibody | |
| Human post synaptic density protein 95 antibody | |
| Post synaptic density protein 95 antibody | |
| Postsynaptic density protein 95 antibody | |
| PSD 95 antibody | |
| PSD-95 antibody | |
| PSD95 antibody | |
| SAP 90 antibody | |
| SAP-90 antibody | |
| SAP90 antibody | |
| Synapse associated protein 90 antibody | |
| Synapse-associated protein 90 antibody | |
| Tax interaction protein 15 antibody |
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Target information
Interacts with the cytoplasmic tail of NMDA receptor subunits and shaker-type potassium channels. Required for synaptic plasticity associated with NMDA receptor signaling. Overexpression or depletion of DLG4 changes the ratio of excitatory to inhibitory synapses in hippocampal neurons. May reduce the amplitude of ASIC3 acid-evoked currents by retaining the channel intracellularly. May regulate the intracellular trafficking of ADR1B. Also regulates AMPA-type glutamate receptor (AMPAR) immobilization at postsynaptic density keeping the channels in an activated state in the presence of glutamate and preventing synaptic depression.
Provider
Erpantech Laboratory