Anti-PSD95 antibody
Specifications
| Product type: | Primary antibody |
| Antigen: | PSD95 |
| Immunogen: | Peptide |
| Species immunized: | Mouse |
| Isotype: | IgG2b |
| Applications: | Immunofluorescence; Western Blot; Immunohistochemistry; Immunocytochemistry; Flow Cytometry |
| Reactivity: | Mouse, Rat and Human |
| Clonality (clone number): | Monoclonal (B5-E6) |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Concentration: | 2mg/ml |
| Purity: | Peptide affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
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Target information
Interacts with the cytoplasmic tail of NMDA receptor subunits and shaker-type potassium channels. Required for synaptic plasticity associated with NMDA receptor signaling. Overexpression or depletion of DLG4 changes the ratio of excitatory to inhibitory synapses in hippocampal neurons. May reduce the amplitude of ASIC3 acid-evoked currents by retaining the channel intracellularly. May regulate the intracellular trafficking of ADR1B. Also regulates AMPA-type glutamate receptor (AMPAR) immobilization at postsynaptic density keeping the channels in an activated state in the presence of glutamate and preventing synaptic depression.
Provider
Erpantech Laboratory