Anti-Progesterone Receptor antibody
Specifications
| Product type: | Primary antibody |
| Antigen: | Progesterone Receptor |
| Immunogen: | Recombinant protein |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:1000); Immunohistochemistry (1:60-1:200); Immunocytochemistry (1:60-1:200) |
| Reactivity: | Human |
| Clonality (clone number): | Monoclonal (JF0549) |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Concentration: | 1mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | NR3C3 antibody |
| Nuclear receptor subfamily 3 group C member 3 antibody | |
| PGR antibody | |
| PR antibody | |
| PRA antibody | |
| PRB antibody | |
| PRGR_HUMAN antibody | |
| Progesterone receptor antibody | |
| Progestin receptor form A antibody | |
| Progestin receptor form B antibody |
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Target information
The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Depending on the isoform, progesterone receptor functions as transcriptional activator or repressor.Curated3 Publications
Isoform A: Ligand-dependent transdominant repressor of steroid hormone receptor transcriptional activity including repression of its isoform B, MR and ER. Transrepressional activity may involve recruitment of corepressor NCOR2.Curated3 Publications
Isoform B: Transcriptional activator of several progesteron-dependent promoters in a variety of cell types. Involved in activation of SRC-dependent MAPK signaling on hormone stimulation.1 Publication
Isoform 4: Increases mitochondrial membrane potential and cellular respiration upon stimulation by progesterone.
Provider
Erpantech Laboratory
