Anti-pro Caspase 9 antibody
Specifications
| Product type: | Primary antibody |
| Antigen: | pro Caspase 9 |
| Immunogen: | Recombinant protein |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:800-1:2000); Immunohistochemistry (1:60-1:200); Flow Cytometry (1:20-1:50) |
| Reactivity: | Human |
| Clonality (clone number): | Monoclonal (JJ08-05) |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Concentration: | 1mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | APAF-3 antibody |
| APAF3 antibody | |
| Apoptotic protease Mch-6 antibody | |
| Apoptotic protease-activating factor 3 antibody | |
| CASP-9 antibody | |
| CASP9 antibody | |
| CASP9_HUMAN antibody | |
| Caspase-9 subunit p10 antibody | |
| ICE-LAP6 antibody | |
| ICE-like apoptotic protease 6 antibody | |
| ICELAP6 antibody | |
| MCH6 antibody |
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Target information
Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP).
Isoform 2 lacks activity is an dominant-negative inhibitor of caspase-9.
Provider
Erpantech Laboratory