Anti-PRDM14 antibody
Specifications
| Product type: | Primary antibody |
| Antigen: | PRDM14 |
| Immunogen: | Peptide |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:600-1:1000); Immunohistochemistry (1:100); Immunocytochemistry (1:100) |
| Reactivity: | Mouse, Human |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Concentration: | 1mg/ml |
| Purity: | Immunogen affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | MGC59730 antibody |
| PFM 11 antibody | |
| PFM11 antibody | |
| PR domain containing 14 antibody | |
| PR domain zinc finger protein 14 antibody | |
| PR domain-containing protein 14 antibody | |
| PRD14_HUMAN antibody | |
| PRDM 14 antibody | |
| PRDM14 antibody |
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Target information
Transcription factor that has both positive and negative roles on transcription. Required for the maintenance of embryonic stem cell identity and the reacquisition of pluripotency in somatic cells. May play an essential role in germ cell development at 2 levels: the reacquisition of potential pluripotency, including SOX2 up-regulation, and successful epigenetic reprogramming, characterized by EHMT1 repression. Its association with CBFA2T2 is required for the functions in pluripotency and germ cell formation (By similarity). Directly up-regulates the expression of pluripotency gene POU5F1 through its proximal enhancer. Binds to the DNA consensus sequence 5′-GGTC[TC]CTAA-3′.
Provider
Erpantech Laboratory
