Anti-Podoplanin antibody
Specifications
| Product Cat#: | AB-06-3635 |
| Product type: | Primary antibody |
| Antigen: | Podoplanin |
| Immunogen: | Recombinant protein |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:2000-1:5000); Immunohistochemistry (1:50-1:200) |
| Reactivity: | Human |
| Clonality (clone number): | Monoclonal (JM31-21) |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4), 1% BSA, 40% Glycerol, 0.05% NaN3. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | Aggrus antibody |
| Glycoprotein 36 KD antibody | |
| Glycoprotein 36 antibody | |
| gp 36 antibody | |
| GP 38 antibody | |
| GP 40 antibody | |
| gp36 antibody | |
| GP38 antibody | |
| GP40 antibody | |
| HT1A 1 antibody | |
| HT1A1 antibody | |
| hT1alpha 1 antibody | |
| hT1alpha 2 antibody | |
| hT1alpha1 antibody | |
| hT1alpha2 antibody | |
| Lung Type I Cell Membrane Associated Glycoprotein antibody | |
| Lung Type I Cell Membrane Associated Glycoprotein Isoform a antibody | |
| Lung Type I Cell Membrane Associated Glycoprotein T1A 2 antibody | |
| OTS 8 antibody | |
| OTS8 antibody | |
| OTTHUMP00000009640 antibody | |
| OTTHUMP00000044504 antibody | |
| PA2.26 antibody | |
| PA2.26 antigen antibody | |
| Pdpn antibody | |
| PDPN_HUMAN antibody | |
| Podoplanin antibody | |
| PSEC0003 antibody | |
| PSEC0025 antibody | |
| T1 Alpha antibody | |
| T1 ALPHA GENE antibody | |
| T1-Alpha antibody | |
| T1A 2 antibody | |
| T1A antibody | |
| TI1A antibody | |
| TIA 2 antibody |
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Target information
Mediates effects on cell migration and adhesion through its different partners. During development plays a role in blood and lymphatic vessels separation by binding CLEC1B, triggering CLEC1B activation in platelets and leading to platelet activation and/or aggregation (PubMed:14522983, PubMed:15231832, PubMed:17616532, PubMed:18215137, PubMed:17222411). Interaction with CD9, on the contrary, attenuates platelet aggregation induced by PDPN (PubMed:18541721). Through MSN or EZR interaction promotes epithelial-mesenchymal transition (EMT) leading to ERZ phosphorylation and triggering RHOA activation leading to cell migration increase and invasiveness (PubMed:17046996, PubMed:21376833).
Provider
Erpantech Laboratory
