Anti-PNKP antibody
Specifications
| Product Cat#: | AB-06-4917 |
| Product type: | Primary antibody |
| Antigen: | PNKP |
| Immunogen: | Synthetic peptide within human PNKP aa 460-509/521. |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:400); Immunohistochemistry-Paraffin (1:100) |
| Reactivity: | Human |
| Clonality (clone number): | Monoclonal, JE64-85 |
| Form: | Liquid |
| Buffer: | 1*TBS buffer (pH7.4), 0.05% BSA, 40% Glycerol, 0.05% NaN3. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified. |
| Storage: | Aliquot and freeze at -20°C. Avoid multiple freeze/thaw cycles. |
| Conjugate: | Unconjugated |
| Alternative names: | 2"(3")-polynucleotidase antibody |
| 2'(3')-polynucleotidase antibody | |
| Bifunctional polynucleotide phosphatase/kinase antibody | |
| DEM 1 antibody | |
| DEM1 antibody | |
| DNA 5' kinase/3' phosphatase antibody | |
| DNA 5"-kinase/3"-phosphatase antibody | |
| EIEE10 antibody | |
| Homo sapiens polynucleotide kinase 3' phosphatase (PNKP) antibody | |
| MCSZ antibody | |
| PNK 1 antibody | |
| PNK1 antibody | |
| Pnkp antibody | |
| PNKP DNA kinase antibody | |
| PNKP_HUMAN antibody | |
| Polynucleotide 3'-phosphatase antibody | |
| Polynucleotide 5' hydroxyl kinase antibody | |
| Polynucleotide 5"-hydroxyl-kinase antibody | |
| Polynucleotide kinase 3 prime phosphatase antibody | |
| Polynucleotide kinase 3' phosphatase antibody | |
| Polynucleotide Kinase antibody | |
| Polynucleotide kinase-3"-phosphatase antibody |
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Target information
Plays a key role in the repair of DNA damage, functioning as part of both the non-homologous end-joining (NHEJ) and base excision repair (BER) pathways. Through its two catalytic activities, PNK ensures that DNA termini are compatible with extension and ligation by either removing 3′-phosphates from, or by phosphorylating 5′-hydroxyl groups on, the ribose sugar of the DNA backbone.
Provider
Erpantech Laboratory