Anti-PI 3 Kinase p85 Beta antibody
Specifications
| Product Cat#: | AB-06-3575 |
| Product type: | Primary antibody |
| Antigen: | PI 3 Kinase p85 Beta |
| Immunogen: | Recombinant protein |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:1000-1:2000); Immunohistochemistry (1:50-1:200); Immunofluorescence; Immunocytochemistry (1:50-1:200); Flow Cytometry (1:100-1:200); Immunoprecipitation |
| Reactivity: | Human, Rat |
| Clonality (clone number): | Monoclonal (ST04-77) |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4), 1% BSA, 40% Glycerol, 0.05% NaN3. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | p85 antibody |
| p85 beta antibody | |
| P85B antibody | |
| P85B_HUMAN antibody | |
| Phosphatidylinositol 3 Kinase antibody | |
| Phosphatidylinositol 3 Kinase Regulatory Beta Subunit antibody | |
| Phosphatidylinositol 3 Kinase Regulatory Subunit Beta antibody | |
| Phosphatidylinositol 3 Kinase Regulatory Subunit Polypeptide 2 antibody | |
| Phosphatidylinositol 3 Kinase, Regulatory Subunit, Polypeptide 2 (p85 Beta) antibody | |
| Phosphatidylinositol 3-Kinase 85 kDa Regulatory Subunit Beta antibody | |
| Phosphatidylinositol 3-Kinase Regulatory Subunit Beta antibody | |
| Phosphoinositide 3 Kinase Regulatory Subunit 2 (Beta) antibody | |
| Phosphoinositide 3 Kinase Regulatory Subunit 2 antibody | |
| Phosphoinositide 3 Kinase Regulatory Subunit Polypeptide 2 (p85 beta) antibody | |
| Phosphoinositide 3 Kinase Regulatory Subunit Polypeptide 2 antibody | |
| Phosphoinositide 3 Kinase, Regulatory Subunit 2 (Beta) antibody | |
| Phosphoinositide 3 Kinase, Regulatory Subunit 2 (p85 Beta) antibody | |
| PI3 Kinase p85 Beta Subunit antibody | |
| PI3 Kinase p85 Subunit Beta antibody | |
| PI3-Kinase regulatory subunit beta antibody | |
| PI3-Kinase Subunit p85-Beta antibody | |
| PI3K antibody | |
| PI3K Regulatory Subunit Beta antibody | |
| PIK3R 2 antibody | |
| PIK3R2 antibody | |
| PtdIns 3 Kinase p85 Beta antibody |
Target information
Regulatory subunit of phosphoinositide-3-kinase (PI3K), a kinase that phosphorylates PtdIns(4,5)P2 (Phosphatidylinositol 4,5-bisphosphate) to generate phosphatidylinositol 3,4,5-trisphosphate (PIP3). PIP3 plays a key role by recruiting PH domain-containing proteins to the membrane, including AKT1 and PDPK1, activating signaling cascades involved in cell growth, survival, proliferation, motility and morphology. Binds to activated (phosphorylated) protein-tyrosine kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Indirectly regulates autophagy (PubMed:23604317). Promotes nuclear translocation of XBP1 isoform 2 in a ER stress- and/or insulin-dependent manner during metabolic overloading in the liver and hence plays a role in glucose tolerance improvement (By similarity).
Provider
Erpantech Laboratory
