Anti-pHyde antibody
Specifications
| Product Cat#: | AB-06-4804 |
| Product type: | Primary antibody |
| Antigen: | pHyde |
| Immunogen: | A synthetic peptide derived from human STEA3. The exact amino-acid sequence is 421-470. |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Immunohistochemistry-Paraffin (1:150-300); Western Blot (1:400-1:2000); Immunofluorescence (1:200-1:500) |
| Reactivity: | Human, Mouse, Rat |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | 1*PBS (pH7.4), 0.5% BSA, 50% glycerol and 0.02% sodium azide. |
| Concentration: | 1 mg/ml |
| Purity: | Immunogen affinity purified. |
| Storage: | Aliquot and freeze at -20°C. Avoid multiple freeze/thaw cycles. |
| Conjugate: | Non-conjugated |
| Alternative names: | STEAP3 antibody; TSAP6 antibody; Metalloreductase STEAP3 antibody; Dudulin-2 antibody; Six-transmembrane epithelial antigen of prostate 3 antibody; Tumor suppressor-activated pathway protein 6 antibody; hTSAP6 antibody; pHyde antibody; hpHyde antibody |
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Target information
Endosomal ferrireductase required for efficient transferrin-dependent iron uptake in erythroid cells. Participates in erythroid iron homeostasis by reducing Fe3+ to Fe2+. Can also reduce of Cu2+ to Cu1+, suggesting that it participates in copper homeostasis. Uses NADP+ as acceptor. May play a role downstream of p53/TP53 to interface apoptosis and cell cycle progression. Indirectly involved in exosome secretion by facilitating the secretion of proteins such as TCTP.
Provider
Erpantech Laboratory
