Anti-Phospho-alpha Synuclein (S129) antibody
Specifications
| Product Cat#: | AB-06-3462 |
| Product type: | Primary antibody |
| Antigen: | Phospho-alpha Synuclein (S129) |
| Immunogen: | Synthetic phospho-peptide corresponding to residues surrounding Ser129 of human alpha Synuclein. |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:400); Immunohistochemistry(1:40-1:200); Immunocytochemistry (1:40-1:200); Immunofluorescence |
| Reactivity: | Human, Mouse, Rat |
| Clonality (clone number): | Monoclonal (JB22-44) |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4), 1% BSA;40% glycerol, 0.05% NaN3. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | Alpha synuclein antibody |
| Alpha-synuclein antibody | |
| Alpha-synuclein, isoform NACP140 antibody | |
| AlphaSYN antibody | |
| MGC105443 antibody | |
| MGC110988 antibody | |
| MGC127560 antibody | |
| MGC64356 antibody | |
| NACP antibody | |
| Non A beta component of AD amyloid antibody | |
| Non A4 component of amyloid antibody | |
| Non A4 component of amyloid precursor antibody | |
| Non-A beta component of AD amyloid antibody | |
| Non-A-beta component of alzheimers disease amyloid , precursor of antibody | |
| Non-A4 component of amyloid precursor antibody | |
| Non-A4 component of amyloid, precursor of antibody | |
| OTTHUMP00000218549 antibody | |
| OTTHUMP00000218551 antibody | |
| OTTHUMP00000218552 antibody | |
| OTTHUMP00000218553 antibody | |
| OTTHUMP00000218554 antibody | |
| PARK1 antibody | |
| PARK4 antibody | |
| PARK1 antibody | |
| PARK4 antibody | |
| Parkinson disease (autosomal dominant, Lewy body) 4 antibody | |
| Parkinson disease familial 1 antibody | |
| SNCA antibody | |
| Snca synuclein, alpha (non A4 component of amyloid precursor) antibody | |
| SYN antibody | |
| Synuclein alpha antibody | |
| Synuclein alpha 140 antibody | |
| Synuclein, alpha (non A4 component of amyloid precursor) antibody |
Target information
Neuronal protein that plays several roles in synaptic activity such as regulation of synaptic vesicle trafficking and subsequent neurotransmitter release. Participates as a monomer in synaptic vesicle exocytosis by enhancing vesicle priming, fusion and dilation of exocytotic fusion pores. Mechanistically, acts by increasing local Ca2+ release from microdomains which is essential for the enhancement of ATP-induced exocytosis.Acts also as a molecular chaperone in its multimeric membrane-bound state, assisting in the folding of synaptic fusion components called SNAREs (Soluble NSF Attachment Protein REceptors) at presynaptic plasma membrane in conjunction with cysteine string protein-alpha/DNAJC5 . This chaperone activity is important to sustain normal SNARE-complex assembly during aging. Plays also a role in the regulation of the dopamine neurotransmission by associating with the dopamine transporter (DAT1) and thereby modulating its activity
Provider
Erpantech Laboratory
