Anti-PDGFB antibody
Specifications
| Product Cat#: | AB-07-3450 |
| Product type: | Primary antibody |
| Antigen: | PDGFB |
| Immunogen: | A synthetic peptide derived from human PDGFB. The exact amino-acid sequence is proprietary. |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | ELISA (1:10000); Western Blot (1:500-1:2500) |
| Reactivity: | Human, Mouse, Rat |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | PBS (without Mg2+ and Ca2+ ), pH 7.4, 0.02% sodium azide and 50% glycerol |
| Concentration: | 1 mg/ml |
| Purity: | Antigen affinity chromatography |
| Storage: | Aliquot and freeze at -20°C. Avoid multiple freeze/thaw cycles. |
| Alternative names: | PDGF2, Oncogene sis, PDGF B chain, Platelet-derived growth factor B chain, Simian sarcomaviral oncogene homolog, SSV PDGFB/COL1A1 fusion gene, V-Sis platelet-derived growth factor beta polypeptide |
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Target information
Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin (PubMed:26599395). Required for normal proliferation and recruitment of pericytes and vascular smooth muscle cells in the central nervous system, skin, lung, heart and placenta. Required for normal blood vessel development, and for normal development of kidney glomeruli. Plays an important role in wound healing. Signaling is modulated by the formation of heterodimers with PDGFA (By similarity).
Provider
Erpantech Laboratory
