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Anti-P63 antibody

SKU Product Brand Unit Availability Price Quantity  
AB-06-3323
Anti-P63 antibody
Erpan Tech In stock

Specifications        

Product type: Primary antibody
Antigen: P63
Immunogen: peptide
Species immunized: Rabbit
Isotype: IgG
Applications: Western Blot (1:600-1:1100); Immunohistochemistry (1:150-1:250)
Reactivity: Human,mouse,rat
Clonality (clone number): Polyclonal
Form: Liquid
Buffer: 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Concentration: 1mg/ml
Purity: Protein  affinity purified
Storage: Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles.
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Target information

Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. Isoform 2 activates RIPK4 transcription. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. Involved in Notch signaling by probably inducing JAG1 and JAG2. Plays a role in the regulation of epithelial morphogenesis. The ratio of DeltaN-type and TA*-type isoforms may govern the maintenance of epithelial stem cell compartments and regulate the initiation of epithelial stratification from the undifferentiated embryonal ectoderm. Required for limb formation from the apical ectodermal ridge. Activates transcription of the p21 promoter.

Provider

Erpantech Laboratory

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