Anti-p16 ARC antibody
Specifications
| Product type: | Primary antibody |
| Antigen: | p16 ARC |
| Immunogen: | recombinant protein |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:1000-1:2000); Immunocytochemistry (1:100-1:200); Immunofluorescence; Immunohistochemistry (1:100-1:200); Immunoprecipitation; Flow Cytometry (1:100-1:200) |
| Reactivity: | Human, Mouse, Rat |
| Clonality (clone number): | Monoclonal(SR34-02) |
| Form: | Liquid |
| Buffer: | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Concentration: | 1mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | Actin related protein 2/3 complex subunit 5 (16 kD) antibody |
| Actin related protein 2/3 complex subunit 5 antibody | |
| Actin related protein 2/3 complex, subunit 5 16kDa antibody | |
| Actin-related protein 2/3 complex subunit 5 antibody | |
| ARC16 antibody | |
| Arp2/3 complex 16 kDa subunit antibody | |
| Arp2/3 protein complex subunit p16 antibody | |
| ARPC 5 antibody | |
| Arpc5 antibody | |
| ARPC5_HUMAN antibody | |
| dJ127C7.3 antibody | |
| MGC88523 antibody | |
| p16 Arc antibody | |
| p16-ARC antibody | |
| RP1 127C7.3 antibody |
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Target information
Component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF) (PubMed:9230079). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility (PubMed:9230079). In addition to its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA (PubMed:29925947). The Arp2/3 complex promotes homologous recombination (HR) repair in response to DNA damage by promoting nuclear actin polymerization, leading to drive motility of double-strand breaks (DSBs) (PubMed:29925947).
Provider
Erpantech Laboratory
