Anti-p130 Cas (Ab-410) antibody
Specifications
| Product Cat#: | AB-07-3398 |
| Product type: | Primary antibody |
| Antigen: | p130 Cas |
| Immunogen: | A synthetic peptide derived from human p130 Cas around the phosphorylation site of tyrosine 410 (G-V-T-A-V). The exact amino-acid sequence is proprietary. |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | ELISA (1:4500); Immunohistochemistry (1:50-1:100); Western Blot (1:500-1:2500) |
| Reactivity: | Human, Mouse, Rat |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | PBS (without Mg2+ and Ca2+ ), pH 7.4, 0.02% sodium azide and 50% glycerol |
| Concentration: | 1 mg/ml |
| Purity: | Antigen affinity chromatography |
| Storage: | Aliquot and freeze at -20°C. Avoid multiple freeze/thaw cycles. |
| Alternative names: | BCAR1, Breast cancer anti-estrogen resistance 1, CRK-ASSOCIATED SUBSTRATE, CRKAS |
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Target information
Docking protein which plays a central coordinating role for tyrosine kinase-based signaling related to cell adhesion. Implicated in induction of cell migration. Overexpression confers antiestrogen resistance on breast cancer cells.
Provider
Erpantech Laboratory
