Anti-OAT antibody
Specifications
| Product Cat#: | AB-07-3388 |
| Product type: | Primary antibody |
| Antigen: | OAT |
| Immunogen: | A synthetic peptide derived from human OAT. The exact amino-acid sequence is proprietary. |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | ELISA (1:1000); Western Blot (1:500-1:2500) |
| Reactivity: | Human, Mouse, Rat |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | PBS (without Mg2+ and Ca2+ ), pH 7.4, 0.02% sodium azide and 50% glycerol |
| Concentration: | 1 mg/ml |
| Purity: | Antigen affinity chromatography |
| Storage: | Aliquot and freeze at -20°C. Avoid multiple freeze/thaw cycles. |
| Alternative names: | DKFZp781A11155; GACR; Gyrate atrophy; HOGA; OAT; OATASE; OKT; Ornithine aminotransferase; Ornithine aminotransferase, hepatic form; Ornithine aminotransferase, mitochondrial; Ornithine |
| aminotransferase, renal form; Ornithine-oxo-acid aminotransferase; Ornithine-delta-aminotransferase; Ornithine-oxo-acid aminotransferase |
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Target information
This gene encodes the mitochondrial enzyme ornithine aminotransferase, which is a key enzyme in the pathway that converts arginine and ornithine into the major excitatory and inhibitory neurotransmitters glutamate and GABA. Mutations that result in a deficiency of this enzyme cause the autosomal recessive eye disease Gyrate Atrophy. Alternatively spliced transcript variants encoding different isoforms have been described. Related pseudogenes have been defined on the X chromosome.
Provider
Erpantech Laboratory
