Anti-NXF1 antibody
Specifications
| Product Cat#: | AB-06-3236 |
| Product type: | Primary antibody |
| Antigen: | NXF1 |
| Immunogen: | Recombinant protein within c-terminal human NXF1. |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:600-1:2000); Immunoprecipitation(1:20-1:50); Immunocytochemistry (1:40-1:100) |
| Reactivity: | Human |
| Clonality (clone number): | Monoclonal (JE40-63) |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4),1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Concentration: | 1 mg/ml |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Purity: | Protein A affinity purified |
| Alternative names: | DKFZp667O0311 antibody |
| DmNXF1 antibody | |
| MEX67 antibody | |
| MEX67, yeast, homolog of antibody | |
| Mex67p antibody | |
| mRNA export factor TAP antibody | |
| Mvb1 antibody | |
| Nuclear RNA export factor 1 antibody | |
| Nuclear RNA export factor 1 homolog (S. cerevisiae) antibody | |
| nxf 1 antibody | |
| NXF1 antibody | |
| NXF1_HUMAN antibody | |
| Protein small bristles antibody | |
| Sbr antibody | |
| TAP antibody | |
| Tip associating protein antibody | |
| Tip-associated protein antibody | |
| Tip-associating protein antibody |
Target information
Involved in the nuclear export of mRNA species bearing retroviral constitutive transport elements (CTE) and in the export of mRNA from the nucleus to the cytoplasm (TAP/NFX1 pathway) (PubMed:10924507). The NXF1-NXT1 heterodimer is involved in the export of HSP70 mRNA in conjunction with ALYREF/THOC4 and THOC5 components of the TREX complex (PubMed:18364396, PubMed:19165146, PubMed:9660949). ALYREF/THOC4-bound mRNA is thought to be transferred to the NXF1-NXT1 heterodimer for export (PubMed:18364396, PubMed:19165146, PubMed:9660949). Also involved in nuclear export of m6A-containing mRNAs: interaction between SRSF3 and YTHDC1 facilitates m6A-containing mRNA-binding to both SRSF3 and NXF1, promoting mRNA nuclear export (PubMed:28984244).
Provider
Erpantech Laboratory