Anti-NR3C2 antibody
Specifications
| Product Cat#: | AB-08-0089 |
| Product type: | Primary antibody |
| Antigen: | NR3C2 |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 800 to the C-terminus of human NR3C2. |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:400-1:2000); Immunofluorescence (1:40-1:200); Immunohistochemistry (1:40-1:200) |
| Reactivity: | Human, Mouse, Rat |
| Clonality: | Polyclonal |
| Form: | Liquid |
| Buffer: | 1*PBS buffer (pH7.3), 50% Glycerol, 0.02% NaN3. |
| Concentration: | 1 mg/ml |
| Purity: | Immoungen affinity purification |
| Storage: | Aliquot and freeze at -20°C. Avoid multiple freeze/thaw cycles. |
| Conjugate: | Unconjugated |
| Alternative names: | NR3C2; MCR; MLR; MR; NR3C2VIT; Mineralocorticoid receptor; Nuclear receptor subfamily 3 group C member 2 |
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Target information
Receptor for both mineralocorticoids (MC) such as aldosterone and glucocorticoids (GC) such as corticosterone or cortisol. Binds to mineralocorticoid response elements (MRE) and transactivates target genes. The effect of MC is to increase ion and water transport and thus raise extracellular fluid volume and blood pressure and lower potassium levels.
Provider
Erpantech Laboratory
