Anti-NME2 antibody
Specifications
| Product Cat#: | AB-06-3161 |
| Product type: | Primary antibody |
| Antigen: | NME2 |
| Immunogen: | Recombinant protein |
| Species immunized: | Mouse |
| Isotype: | IgG |
| Applications: | Immunohistochemistry (1:20-1:200); Western Blot (1:200-1:2000) |
| Reactivity: | Human |
| Clonality (clone number): | Monoclonal(A8-G7) |
| Form: | Liquid |
| Buffer: | 1*TBS (pH7.4), 1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | C myc purine binding transcription factor PUF antibody |
| C myc transcription factor antibody | |
| C-myc purine-binding transcription factor PUF antibody | |
| Epididymis secretory sperm binding protein Li 155an antibody | |
| HEL-S-155an antibody | |
| Histidine protein kinase NDKB antibody | |
| MGC111212 antibody | |
| MGC2212 antibody | |
| NDK B antibody | |
| NDKB antibody | |
| NDKB_HUMAN antibody | |
| NDP kinase B antibody | |
| NDPK B antibody | |
| NDPKB antibody | |
| NM23 H2 antibody | |
| nm23-H2 antibody | |
| NM23B antibody | |
| NME/NM23 nucleoside diphosphate kinase 2 antibody | |
| Nme2 antibody | |
| Non metastatic cells 2, protein (NM23B) expressed in antibody | |
| Non-metastatic cells 2, protein (NM23) expressed in antibody | |
| Nucleoside diphosphate kinase B antibody | |
| Nucleotide diphosphate kinase B antibody | |
| PUF antibody |
Target information
Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity). Negatively regulates Rho activity by interacting with AKAP13/LBC . Acts as a transcriptional activator of the MYC gene; binds DNA non-specifically . Binds to both single-stranded guanine- and cytosine-rich strands within the nuclease hypersensitive element (NHE) III1 region of the MYC gene promoter. Does not bind to duplex NHE III1 . Has G-quadruplex (G4) DNA-binding activity, which is independent of its nucleotide-binding and kinase activity. Binds both folded and unfolded G4 with similar low nanomolar affinities. Stabilizes folded G4s regardless of whether they are prefolded or not. Exhibits histidine protein kinase activity.
Provider
Erpantech Laboratory