Anti-NFIB/NF1B2 antibody
Specifications
| Product Cat#: | AB-06-3118 |
| Product type: | Primary antibody |
| Antigen: | NFIB/NF1B2 |
| Immunogen: | Recombinant full length protein corresponding to human NFIB/NF1B2. |
| Species immunized: | Mouse |
| Isotype: | IgG |
| Applications: | Western Blot (1:200-1:2000); Immunohistochemistry (1:100-1:200); Flow Cytometry (1:100-1:200) |
| Reactivity: | Mouse, Rat and Human |
| Clonality (clone number): | Monoclonal(1H5) |
| Form: | Liquid |
| Buffer: | 1*TBS (pH7.4), 0.5% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide. |
| Concentration: | 2 mg/ml |
| Purity: | Protein G affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | CCAAT Box Binding Transcription Factor antibody |
| CCAAT-box-binding transcription factor antibody | |
| CTF antibody | |
| HMGIC/NFIB antibody | |
| NF-I/B antibody |
Target information
NF-1, also designated CTF, consists of a family of CCAAT box binding proteins that stimulate DNA replication and activate transcription. Analysis of human NF-1 messenger RNA has revealed two forms of the NF-1 protein arising from an alternate splicing of a single NF-1 gene. NF-1 binds its consensus DNA element as a homodimer via an amino-terminal DNA binding domain, and activates transcription through a putatively novel, proline-rich, carboxy terminal transactivation domain. The NF-1 protein has been shown to recognize and bind the adenovirus type 2 promoter and activate transcription of herpes simplex virus thymidine kinase genes. The NF-1 consensus element has been found in the upstream promoter region of myriad eukaryotic genes, including that of Ha-Ras, α-globin, HSP 70, GRP 78, Histone H1, myelin basic protein and in the Xenopus laevis vitellogenin gene promoter.
Provider
Erpantech Laboratory
