Anti-NEDD8 antibody
Specifications
| Product Cat#: | AB-06-3078 |
| Product type: | Primary antibody |
| Antigen: | NEDD8 |
| Immunogen: | Recombinant protein |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot ( 1:400-1:1500 );Immunocytochemistry ( 1:500-1:15 );Flow Cytometry ( 1:50-1:200 ) |
| Reactivity: | Human |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | 1*TBS ( pH7.4 ), 0.5 %BSA, 50 %Glycerol. Preservative: 0.05 % Sodium Azide. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | FLJ43224 Antibody |
| MGC104393 Antibody | |
| MGC125896 Antibody | |
| MGC125897 Antibody | |
| NED8 Antibody | |
| NEDD 8 Antibody | |
| NEDD-8 Antibody | |
| Nedd8 Antibody | |
| NEDD8_HUMAN Antibody | |
| Neddylin Antibody | |
| Neural Precursor Cell Expressed Developmentally Down Regulated 8 Antibody |
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Target information
Ubiquitin-like protein which plays an important role in cell cycle control and embryogenesis. Covalent attachment to its substrates requires prior activation by the E1 complex UBE1C-APPBP1 and linkage to the E2 enzyme UBE2M. Attachment of NEDD8 to cullins activates their associated E3 ubiquitin ligase activity, and thus promotes polyubiquitination and proteasomal degradation of cyclins and other regulatory proteins.
Provider
Erpantech Laboratory
