Anti-Myosin Light Chain 2 Recombinant Rabbit Monoclonal antibody
Specifications
| Product Cat#: | AB-06-3032 |
| Product type: | Primary antibody |
| Antigen: | Myosin Light Chain 2 |
| Immunogen: | Synthetic peptide within Human Myosin Light Chain 2 AA 117-166 / 166. |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:500-1:5000); Immunohistochemistry (1:50-1:200); Immunoprecipitation |
| Reactivity: | Human, Mouse, Rat, Zebrafish |
| Clonality (clone number): | Monoclonal (SN67-09) |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4), 0.05% BSA, 40% Glycerol, 0.05% NaN3 |
| Concentration: | 1 mg/ml |
| Purity: | Peptide affinity purified |
| Storage: | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles |
| Alternative names: | Cardiac myosin light chain-2 antibody |
| Cardiac ventricular myosin light chain 2 antibody | |
| CMH10 antibody | |
| MLC 2v antibody | |
| MLC-2 antibody | |
| MLC-2v antibody | |
| MLC2 antibody | |
| MLRV_HUMAN antibody | |
| MYL 2 antibody | |
| MYL2 antibody | |
| Myosin light chain 2 regulatory cardiac slow antibody | |
| Myosin light polypeptide 2 regulatory cardiac slow antibody | |
| Myosin regulatory light chain 2 antibody | |
| Myosin regulatory light chain 2 ventricular/cardiac muscle isoform antibody | |
| Regulatory light chain of myosin antibody | |
| RLC of myosin antibody | |
| Slow cardiac myosin regulatory light chain 2 antibody | |
| Ventricular/cardiac muscle isoform antibody |
Target information
Contractile protein that plays a role in heart development and function (By similarity). Following phosphorylation, plays a role in cross-bridge cycling kinetics and cardiac muscle contraction by increasing myosin lever arm stiffness and promoting myosin head diffusion; as a consequence of the increase in maximum contraction force and calcium sensitivity of contraction force. These events altogether slow down myosin kinetics and prolong duty cycle resulting in accumulated myosins being cooperatively recruited to actin binding sites to sustain thin filament activation as a means to fine-tune myofilament calcium sensitivity to force (By similarity). During cardiogenesis plays an early role in cardiac contractility by promoting cardiac myofibril assembly (By similarity).
Provider
Erpantech Laboratory