Anti-MTTFA antibody
Specifications
| Product Cat#: | AB-06-2993 |
| Product type: | Primary antibody |
| Antigen: | MTTFA |
| Immunogen: | KLH conjugated synthetic peptide derived from human MTSS1 101-200/755 |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:200-1:500); Immunoprecipitation (1:10-1:50); Immunohistochemistry (1:50-1:200); Immunofluorescence (1:50-1:200); Immunocytochemistry (1:50-1:200) |
| Reactivity: | Human |
| Clonality (clone number): | Monoclonal (JM32-44) |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4), 1% BSA, 40% Glycerol, 0.05% NaN3. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles |
| Alternative names: | Anscription factor 6-like 1 antibody |
| Mitochondrial transcription factor 1 antibody | |
| Mitochondrial transcription factor A antibody | |
| MtTF1 antibody | |
| MtTFA antibody | |
| TCF 6 antibody | |
| TCF-6 antibody | |
| TCF6 antibody | |
| TCF6L1 antibody | |
| TCF6L2 antibody | |
| TCF6L3 antibody | |
| TFAM antibody | |
| TFAM_HUMAN antibody | |
| Transcription factor 6 antibody | |
| Transcription factor 6 like 2 (mitochondrial transcription factor) antibody | |
| Transcription factor 6 like 2 antibody | |
| Transcription factor 6-like 2 antibody | |
| Transcription factor 6-like 3 antibody | |
| Transcription factor A, mitochondrial antibody | |
| Transcription factor A, mitochondrial antibody | |
| Transcription factor A, mitochondrial precursor antibody |
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Target information
Binds to the mitochondrial light strand promoter and functions in mitochondrial transcription regulation (PubMed:29445193). Required for accurate and efficient promoter recognition by the mitochondrial RNA polymerase. Promotes transcription initiation from the HSP1 and the light strand promoter by binding immediately upstream of transcriptional start sites. Is able to unwind DNA. Bends the mitochondrial light strand promoter DNA into a U-turn shape via its HMG boxes. Required for maintenance of normal levels of mitochondrial DNA. May play a role in organizing and compacting mitochondrial DNA.
Provider
Erpantech Laboratory