Anti-Mst3 antibody
Specifications
| Product Cat#: | AB-06-2970 |
| Product type: | Primary antibody |
| Antigen: | Mst3 |
| Immunogen: | Amino acids 275-393 of MST-3 of human origin |
| Species immunized: | Mouse |
| Isotype: | IgG1 |
| Applications: | Western Blot (1:100-1:1000); Immunoprecipitation (1-2 μg per 100-500 μg of total protein(1 ml of cell lysate) ); Immunofluorescence (1:50-1:500) |
| Reactivity: | Human, Mouse, Rat |
| Clonality (clone number): | Monoclonal (1G8) |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4), 1% BSA, 40% Glycerol, 0.05% NaN3. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles |
| Alternative names: | epididymis secretory protein Li 95 antibody |
| HEL-S-95 antibody | |
| Mammalian STE20 like protein kinase 3 antibody | |
| Mammalian STE20-like protein kinase 3 antibody | |
| Mammalian STE20-like protein kinase 3 C-terminal antibody | |
| Mammalian STE20-like protein kinase 3 N-terminal antibody | |
| Mammalian sterile 20-like 3 antibody | |
| MST-3 antibody | |
| MST3/C antibody | |
| MST3/N antibody | |
| MST3B antibody | |
| serine threonine kinase 24 antibody | |
| Serine/threonine kinase 24 (Ste20, yeast homolog) antibody | |
| Serine/threonine-protein kinase 24 12 kDa subunit antibody | |
| Serine/threonine-protein kinase 24 antibody | |
| STE20 homolog yeast antibody | |
| STE20 like kinase MST3 antibody | |
| STE20-like kinase MST3 antibody | |
| Stk24 antibody | |
| STK24_HUMAN antibody | |
| STK3 antibody |
Target information
Serine/threonine-protein kinase that acts on both serine and threonine residues and promotes apoptosis in response to stress stimuli and caspase activation. Mediates oxidative-stress-induced cell death by modulating phosphorylation of JNK1-JNK2 (MAPK8 and MAPK9), p38 (MAPK11, MAPK12, MAPK13 and MAPK14) during oxidative stress. Plays a role in a staurosporine-induced caspase-independent apoptotic pathway by regulating the nuclear translocation of AIFM1 and ENDOG and the DNase activity associated with ENDOG. Phosphorylates STK38L on ‘Thr-442’ and stimulates its kinase activity. In association with STK26 negatively regulates Golgi reorientation in polarized cell migration upon RHO activation (PubMed:27807006). Regulates also cellular migration with alteration of PTPN12 activity and PXN phosphorylation: phosphorylates PTPN12 and inhibits its activity and may regulate PXN phosphorylation through PTPN12. May act as a key regulator of axon regeneration in the optic nerve and radial nerve.
Provider
Erpantech Laboratory