Anti-MPZL antibody
Specifications
| Product Cat#: | AB-06-2942 |
| Product type: | Primary antibody |
| Antigen: | MPZL |
| Immunogen: | KLH conjugated synthetic peptide derived from human MPZL 61-160/269 |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:500-1:2000) |
| Reactivity: | Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | 10 mM Tris-HCl buffer (pH7.4), 1% BSA, 50% Glycerol, 0.03% Proclin300. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles |
| Alternative names: | immunoglobulin family transmembrane protein |
| MPZL1 | |
| MPZL1b | |
| MPZL1_HUMAN | |
| myelin protein zero like 1 | |
| myelin protein zero like protein 1 precursor | |
| myelin protein zero like protein MPZL1b | |
| OTTHUMP00000032519 | |
| Protein zero related | |
| PZR | |
| PZR1b | |
| PZRa |
Show More
Target information
Cell surface receptor, which is involved in signal transduction processes. Recruits PTPN11/SHP-2 to the cell membrane and is a putative substrate of PTPN11/SHP-2. Is a major receptor for concanavalin-A (ConA) and is involved in cellular signaling induced by ConA, which probably includes Src family tyrosine-protein kinases. Isoform 3 seems to have a dominant negative role; it blocks tyrosine phosphorylation of MPZL1 induced by ConA. Isoform 1, but not isoform 2 and isoform 3, may be involved in regulation of integrin-mediated cell motility.
Provider
Erpantech Laboratory
