Anti-MNAT1 antibody
Specifications
| Product Cat#: | AB-06-2924 |
| Product type: | Primary antibody |
| Antigen: | MNAT1 |
| Immunogen: | KLH conjugated synthetic peptide derived from human MNAT1 51-150/309 |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:500-1:2000) |
| Reactivity: | Human |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | 10 mM Tris-HCl buffer (pH7.4), 1% BSA, 50% Glycerol, 0.03% Proclin300. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles |
| Alternative names: | MNAT 1 |
| CAP35 | |
| CDK activating kinase assembly factor MAT1 | |
| CDK7/cyclin H assembly factor | |
| Cyclin G1 interacting protein | |
| MAT1 | |
| Menage a trois | |
| MNAT 1 | |
| p35 | |
| p36 | |
| RING finger protein 66 | |
| RING finger protein MAT1 | |
| RNF66 |
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Target information
Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. CAK activates the cyclin-associated kinases CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminal domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. Involved in cell cycle control and in RNA transcription by RNA polymerase II.
Provider
Erpantech Laboratory
