Anti-MMP14 antibody
Specifications
| Product Cat#: | AB-06-2908 |
| Product type: | Primary antibody |
| Antigen: | MMP14 |
| Immunogen: | Recombinant protein |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:1000); Immunohistochemistry (1:50-1:200); Immunocytochemistry (1:100-1:500); Flow Cytometry (1:50-1:100); Immunoprecipitation; Immunofluorescence |
| Reactivity: | Human, Mouse, Rat |
| Clonality (clone number): | Monoclonal (3-F7) |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4), 1% BSA, 40% Glycerol, 0.05% NaN3. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles |
| Alternative names: | Matrix metallopeptidase 14 (membrane inserted) antibody |
| Matrix metalloproteinase 14 antibody | |
| Matrix metalloproteinase-14 antibody | |
| Membrane type 1 matrix metalloproteinase antibody | |
| Membrane type 1 metalloprotease antibody | |
| Membrane type matrix metalloproteinase 1 antibody | |
| Membrane-type matrix metalloproteinase 1 antibody | |
| Membrane-type-1 matrix metalloproteinase antibody | |
| MMP 14 antibody | |
| MMP X1 antibody | |
| MMP-14 antibody | |
| MMP-X1 antibody | |
| Mmp14 antibody | |
| MMP14_HUMAN antibody | |
| MMPX1 antibody | |
| MT MMP 1 antibody | |
| MT-MMP 1 antibody | |
| MT1 MMP antibody | |
| MT1-MMP antibody | |
| MT1MMP antibody | |
| MTMMP 1 antibody | |
| MTMMP1 antibody |
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Target information
Endopeptidase that degrades various components of the extracellular matrix such as collagen. Activates progelatinase A. Essential for pericellular collagenolysis and modeling of skeletal and extraskeletal connective tissues during development (By similarity). May be involved in actin cytoskeleton reorganization by cleaving PTK7 (PubMed:20837484). Acts as a positive regulator of cell growth and migration via activation of MMP15. Involved in the formation of the fibrovascular tissues in association with pro-MMP2 (PubMed:12714657). Cleaves ADGRB1 to release vasculostatin-40 which inhibits angiogenesis (PubMed:22330140).
Provider
Erpantech Laboratory