Anti-MiTF antibody
Specifications
| Product Cat#: | AB-06-2892 |
| Product type: | Primary antibody |
| Antigen: | MiTF |
| Immunogen: | Recombinant protein |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:1000-1:2000); Immunocytochemistry (1:100-1:500); Flow Cytometry (1:50-1:100) |
| Reactivity: | Human, Mouse, Rat |
| Clonality (clone number): | Monoclonal (JF100-01) |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4), 1% BSA, 40% Glycerol, 0.05% NaN3. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles |
| Alternative names: | BHLHE32 antibody |
| bHLHe32 antibody | |
| Class E basic helix-loop-helix protein 32 antibody | |
| CMM8 antibody | |
| Homolog of mouse microphthalmia antibody | |
| Mi antibody | |
| Microphthalmia associated transcription factor antibody | |
| Microphthalmia, mouse, homolog of antibody | |
| Microphthalmia-associated transcription factor antibody | |
| MITF antibody | |
| MITF_HUMAN antibody | |
| Mitfa antibody | |
| Nacre antibody | |
| WS2 antibody | |
| WS2A antibody | |
| Z3A.1 antibody |
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Target information
Transcription factor that regulates the expression of genes with essential roles in cell differentiation, proliferation and survival. Binds to M-boxes (5′-TCATGTG-3′) and symmetrical DNA sequences (E-boxes) (5′-CACGTG-3′) found in the promoters of target genes, such as BCL2 and tyrosinase (TYR). Plays an important role in melanocyte development by regulating the expression of tyrosinase (TYR) and tyrosinase-related protein 1 (TYRP1). Plays a critical role in the differentiation of various cell types, such as neural crest-derived melanocytes, mast cells, osteoclasts and optic cup-derived retinal pigment epithelium.
Provider
Erpantech Laboratory