Anti-MED12/Trap230 antibody
Specifications
| Product Cat#: | AB-06-2843 |
| Product type: | Primary antibody |
| Antigen: | MED12/Trap23 |
| Immunogen: | KLH conjugated synthetic peptide derived from human MED12/Trap230 251-350/2177 |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:500-1:2000); Immunohistochemistry-Paraffin (1:400-1:800) |
| Reactivity: | Human, Mouse, Rat, Pig, Cow, Rabbit, Sheep |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | 10 mM TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles |
| Alternative names: | Activator recruited cofactor 240 kDa component |
| Activator-recruited cofactor 240 kDa component | |
| Activator-recruited cofactor 240 kDa component | |
| ARC240 | |
| CAG repeat protein 45 | |
| CAGH45 | |
| HOPA | |
| KIAA0192 | |
| MED12 | |
| MED12_HUMAN | |
| Mediator complex subunit 12 | |
| Mediator of RNA polymerase II transcription subunit 12 | |
| Mediator of RNA polymerase II transcription subunit 12 | |
| Mediator of RNA polymerase II transcription subunit 12 | |
| OPA containing protein | |
| OPA-containing protein | |
| OPA-containing protein | |
| Thyroid hormone receptor associated protein complex 230 kDa component | |
| Thyroid hormone receptor-associated protein complex 230 kDa component | |
| Thyroid hormone receptor-associated protein complex 230 kDa component | |
| TNRC11 | |
| Trap230 | |
| Trinucleotide repeat containing gene 11 protein | |
| Trinucleotide repeat-containing gene 11 protein |
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Target information
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. This subunit may specifically regulate transcription of targets of the Wnt signaling pathway and SHH signaling pathway.
Provider
Erpantech Laboratory
