Anti-MED12 antibody
Specifications
| Product Cat#: | AB-07-0776 |
| Immunogen: | A synthetic peptide derived from human MED12. The exact amino-acid sequence is proprietary. |
| Antigen: | MED12 |
| Product type: | Primary antibody |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | ELISA (1:20000); Immunohistochemistry (1:50~1:100) |
| Reactivity: | Human |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Concentration: | 1 mg/ml |
| Purity: | Antigen affinity chromatography |
| Storage: | Aliquot and freeze at -20°C. Avoid multiple freeze/thaw cycles. |
| Alternative names: | Thyroid hormone receptor-associated protein complex 230 kDa component; Trap230;Activator-recruited cofactor 240 kDa component; ARC240; CAG repeat protein 45; OPA-containing protein; Trinucleotide repeat-containing gene 11 protein |
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Target information
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. This subunit may specifically regulate transcription of targets of the Wnt signaling pathway and SHH signaling pathway.
Provider
Erpantech Laboratory
